无动力性骨病（adynamic bone disease， ABD）是慢性肾脏病-矿物质与骨异常的常见类型，其特点是骨转运和骨重塑降低，临床上低甲状旁腺素（parathyroid hormone，PTH）血症是其重要特征。瘤样钙质沉着症（tumoral calcinosis， TC） 是一种表现为软组织和关节周围结构广泛钙化的罕见良性病变，但其确切发病机制尚不清楚。尿毒症瘤样钙质沉着症（uraemic tumoral calcinosis，UTC）在透析患者中虽然发生率较低，但对患者的生活质量、预后会带来严重的不利影响。该文报道了2例ABD合并UTC患者，其中1例患者TC累及双手、双足、双肩胛骨、胸锁关节、髂骨、股骨头、骶尾部，另1例患者TC累及左肩。经重组人PTH特立帕肽注射液皮下注射、硫代硫酸钠静滴、降磷、充分透析等治疗，患者好转。

Adynamic bone disease (ABD) is a common type of chronic kidney disease-mineral and bone disorder (CKD-MBD). It is characterized by decreased bone transport and bone remodeling. Clinically, low parathyroid hormone (PTH) is an important feature of ABD. Tumoral calcinosis (TC) is a rare benign lesion characterized by extensive calcification of soft tissue and periarticular structures, but its exact pathogenesis is still unclear. Although the incidence of uremic tumoral calcinosis (UTC) in dialysis patients is low, it has a serious adverse impact on the quality of life and prognosis of patients. This paper reports two patients with ABD complicated with UTC. One patient had TC involving both hands, both feet, both scapulae, sternoclavicular joint, ilium, femoral head and sacrococcygeal region, and the other patient had TC involving the left shoulder. After treatment with recombinant human PTH teriparatide injection, sodium thiosulfate, phosphorus reduction, and full dialysis, the patients' condition improved.