The awareness rate, treatment rate and control rate of mineral and bone disorder in patients with moderate or advanced stage chronic kidney disease
YAN Jia-yi, ZHANG Min-fang, NI Zhao-hui, JIANG Rong, ZHANG Hai-fen, YAN Yu-cheng, ZHANG Wei-ming, HUANG Jia-ying, FANG Wei, MOU Shan, WANG Qin, QIAN Jia-qi.
Author information+
Renal Division, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, ChinaCorresponding author: ZHANG Min-fang, Email: minfangzh@126.com
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History+
Received
Revised
Published
1900-01-01
1900-01-01
2012-01-15
Issue Date
2012-01-15
Abstract
Objective To investigate the awareness rate, treatment rate and control rate of mineral and bone disorder in patients with moderate or advanced stage chronic kidney disease (CKD). Methods The awareness rate, treatment rate and control rate of mineral and bone disorder were evaluated based on a questionnaire and related laboratory examinations in 503 CKD stage 3 to 5 patients. Results The awareness rate of mineral and bone disorder in patients with moderate or advanced stage CKD was highest in hemodialysis patients, moderate in peritoneal dialysis patients and lowest in non-dialyzed patients (all P<0.01). The total scores of the questionnaire were lowest in non-dialyzed patients [6(5,8)] and were significantly higher in peritoneal dialysis [11(9,12)] and hemodialysis patients [13(11,15)] (P<0.01). The extent of awareness was negatively correlated with age (r=-0.11, P<0.05), and positively correlated with educational background (r=0.226, P<0.01), duration of CKD (r=0.597, P<0.01) and duration of dialysis (r=0.366, P<0.01). The source of knowledge was mainly from publicity and education made by medical staff, which accounted for 94.0%, 79.5% and 69.4% respectively in non-dialyzed, peritoneal dialysis and hemodialysis patients. The treatment rate was significantly higher in peritoneal dialysis (88.6%) and hemodialysis patients (96.9%) than that in non-dialyzed patients (58.2%) (all P<0.01). According to K/DOQI guideline, the control rate of serum calcium, phosphorus, calcium and phosphorus product and parathyroid hormone (PTH) were much better in non-dialyzed patients as compared to dialyzed ones. The percentage of number of lab indicators meeting the standard was significantly higher in non-dialyzed patients as compared to dialyzed ones (P<0.01). According to KDIGO guideline, the control rate of serum phosphorus was significantly lower in hemodialysis patients (23.6%) than that in peritoneal dialysis (36.9%) and non-dialyzed patients (46.7%) (P<0.01). Conclusions In non-dialyzed patients with moderate or advanced stage CKD, the awareness rate and treatment rate of mineral and bone disorder are relatively low, and the control rate is relatively high. Whereas in dialyzed patients, the awareness rate and treatment rate are relatively high, and the control rate is relatively low.
YAN Jia-yi;ZHANG Min-fang;NI Zhao-hui;JIANG Rong;ZHANG Hai-fen;YAN Yu-cheng;ZHANG Wei-ming;HUANG Jia-ying;FANG Wei;MOU Shan;WANG Qin;QIAN Jia-qi. .
The awareness rate, treatment rate and control rate of mineral and bone disorder in patients with moderate or advanced stage chronic kidney disease [J]. Chinese Journal of Nephrology, 2012, 28(1): 10-15.
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